MOLECULAR NETWORK ANALYSIS SUGGESTS A LOGICAL HYPOTHESIS FOR THE PATHOLOGICAL ROLE OF C9ORF72 IN AMYOTROPHIC LATERAL SCLEROSIS/FRONTOTEMPORAL DEMENTIA

Background Expanded GGGGCC hexanucleotide repeats, ranging from hundreds to thousands in number, located in the noncoding region of the chromosome 9 open reading frame 72 ( C9orf72 ) gene represent the most common genetic abnormality for familial and sporadic amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) (abbreviated as C9AL

We studied the activity budgets of seven Ailurus fulgens, at three zoos within Australasia, using video cameras, and in-person observations.Red panda in this study followed a crepuscular activity pattern, with another short peak of activity around midnight.Ambient temperature greatly Rolling affected panda activity patterns; red panda allocated mor

Abstract Background Where resources are available, the World Health Organization recommends cervical cancer screening with human papillomavirus (HPV) DNA testing and subsequent treatment of HPV-positive women with timely cryotherapy.Newer technologies may facilitate a same-day screen-and-treat approach, but these testing systems are generally too e

BACKGROUND:Cigarette smoking is reported to decrease survival and induce chemotherapy resistance in patients with various cancers.However, the impact of cigarette smoking on patients with esophageal squamous cell carcinoma (ESCC) remains unknown.METHODS:A total of 1,084 ESCC patients were retrospectively enrolled from a southern Chinese institution

Increasing population and the rising air temperatures are known as factors that cause water depletion in the watersheds.Therefore, it is important to accurately predict the future ratios of tap water consumers using the same watershed to the population living in the specified area, to produce better water policies and to Floor Runners take the nece